VDSpher® OptiBio Phases

VDSpher OptiBio phases have been developed specially for biochemical analysis such as protein and peptide separation. OptiBio separation phases with different modifications are available, suitable for a broad range of applications. The available VDSpher OptiBio PUR reversed phase modifications are shown in the Table.

Analytes that can be examined with VDSpher OptiBio columns are e.g., antibodies, oligo-nucleotides, peptides and proteins as well as other biomolecules. Depending on the pore diameter of the VDSpher OptiBio phase, analytes of different sizes and structures can be handled.

All VDSpher OptiBio modifications are pH-stable over a wide range and can be used without any problem up to a temperature of 65 °C. Eluents with high water content can be used for all phases.

The various modifications differ in terms of hydrophobicity as shown in the Figure below using the example of C18 phases.

Hydrophobicity of VDSpher® OptiBio C18 modifications.

The available particle sizes can be obtained from our current price list.

VDSpher OptiBio phases can also be filled in biocompatible PEEK columns upon request.

Reversed Phase Modifications: VDSpher® OptiBio & OptiBio PUR Phases

Phase available
Pore sizes
[Å]
Endcapping pH range Max. H2O-
proportion
[%]
USP Code
OptiBio PUR C18-E 300 yes 2 - 8 90 L1

OptiBio PUR C18-SE

300 yes (special) 2 - 9 95 L1
OptiBio PUR C18-M-E 300 yes 2 - 8 100 L1
OptiBio PUR C18-M-SE 300 yes (special) 2 - 9 100 L1
OptiBio PUR C8-E 300 yes 2 - 7.5 90 L7
OptiBio PUR C8-SE 300

yes (special)

2 - 9 95 L7
OptiBio PUR C8-M-E 300 yes 2 - 8 100 L7
OptiBio PUR C8-M-SE 300

yes (special)

2 - 9

100 L7
OptiBio PUR C4-E 300 yes 2 - 8 90 L26
OptiBio PUR C4-SE

300

yes (special) 2 - 9 95 L26
OptiBio PUR C4-M-SE 300 yes

2 - 8

100 L26
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