VDSpher® OptiAqua Phases

VDSpher OptiAqua phases have been developed especially for very hydrophilic applications. Special polar endcapping makes it possible to use 100% water as solvent while still maintaining RP properties.

Six VDSpher OptiAqua phases with different modifications as well as pore sizes and particle diameters have been developed on the basis of VDSpher Classic and VDSpher PUR, with which a large number of applications can be implemented. Ideal preconditions therefore exist for preparative as well as the analytical HPLC.

Analytes of different sizes can also be handled optimally. Thus, different molar mass ranges can be covered, depending on the pore size of the modified silica gel. The available VDSpher OptiAqua & OptiAqua PUR reversed phase modifications are shown in the Table.

VDSpher OptiAqua phases can also be used to separate polar substances. Examples of typical analytes include:

  • antibiotics
  • biomolecules
  • drugs
  • nucleobases
  • organic acids
  • parabens
  • pesticides
  • sulfonamides
  • water-soluble vitamines
  • xanthines

All VDSpher OptiAqua phases are pH stable in a range of 2 to 7.5 and can be used without any problem up to a temperature of 60 °C.

Reversed Phase Modifications: VDSpher® OptiAqua & OptiAqua PUR

Phase Available
Pore sizes
Carbon content
Analyte size
USP Code
OptiAqua C18 100 13.0 30 - 800 L1
OptiAqua C8 100


30 - 800 L7
OptiAqua PUR C18 100, 150 100 Å: 13.0
150 Å: 7.0
100 Å: 30 - 800
150 Å: 120 - 3200
OptiAqua PUR C8 100 8.1 30 - 800 L7

The available particle sizes can be obtained from our current price list.

VDSpher OptiAqua PUR C4 on request.

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